凯文·史派西
Kevin Spacey
饰：普洛特 Prot
杰夫·布里吉斯
Jeff Bridges
饰：马克•鲍威尔医生 Dr. Mark Powell
玛丽·麦克科马克
Mary Catherine McCormack
饰：Rachel Powell
兰斯·E·尼克尔斯
Lance E. Nichols
饰：David Patel (as Lance Nichols)
文森特·拉斯卡
Vincent Laresca
饰：Navarro
威廉姆·拉金
William Lucking
饰：Sheriff
布莱恩·豪威
Brian Howe
饰：Steve
亚伦·保尔
Aaron Paul
饰：Michael Powell (Age 21)
西莉亚·韦斯顿
Celia Weston
饰：Doris Archer
诺曼·阿尔登
Norman Alden
饰：Babbling Man
彼得·马洛尼
Peter Maloney
饰：Duncan Flynn
弗兰克·考利森
Frank Collison
饰：Screaming Man (uncredited)
金伯利·斯科特
Kimberly Scott
饰：Joyce Trexler
阿尔法·伍达德
Alfre Woodard
饰：Dr. Claudia Villars
大卫·帕特里克·凯利
David Patrick Kelly
饰：Howie
索尔·威廉姆斯
Saul Williams
饰：Ernie
彼德·格雷迪
Peter Gerety
饰：Sal
阿杰·奈杜
Ajay Naidu
饰：Dr. Chakraborty
特雷西·维拉尔
Tracy Vilar
饰：Maria
John Toles-Bey
John Toles-Bey
饰：Russell
康查塔·弗丽尔
Conchata Ferrell
饰：Betty McAllister
马克·克里斯托弗·劳伦斯
Mark Christopher Lawrence
饰：Simms
玛丽·马拉
Mary Mara
饰：Abby
Brandon de Paul
饰：Josh (Age 10) (as Brandon Michael Depaul)
Kelly Connell
饰：Walter Fleen
Paul Linke
饰：Stuart Hessler
Greg Lewis
Greg Lewis
饰：Dominic McAllister
克拉克·彼得斯
Clarke Peters
饰：Homeless Veteran
欧嘉·梅雷迪斯
Olga Merediz
饰：Transit Officer
洛拉·帕沙林斯基
Lola Pashalinski
饰：Russian Woman
Kateri Walker
Kateri Walker
饰：Sara Porter
Scott Lincoln
Scott Lincoln
饰：Walker
克莱伯特·福特
Clebert Ford
饰：Homeless Man
Rawle D. Lewis
Rawle D. Lewis
饰：Security Guard
Eric LaRay Harvey
饰：Security Guard
索菲娅·博鲁卡
Zofia Borucka
饰：Woman on Train
Tony Rhune
饰：Thug
Vince Capone
Vince Capone
饰：Thug (as Vincent Capone)
Lisa Cohen
Lisa Cohen
饰：Ward Patient
Clete Francis
饰：Ward Patient
Pat Jankiewicz
饰：Ward Patient
Josef S. Klus
Josef S. Klus
饰：Ward Patient (as Josef Klus)
Coco Leigh
Coco Leigh
饰：Ward Patient
Moet Meira
饰：Jennifer (uncredited)
Elizabeth Woodward
饰：Woman #1 (uncredited)
Melanee Murray
饰：Bess
Tess McCarthy
饰：Natalie Powell (Age 6)
Natasha Dorfhuber
饰：Gabby Powell (Age 9)
泰德·霍利斯
Ted Hollis
饰：Ward Doctor (uncredited)
柯特·克伦德尼
Curt Clendenin
饰：Hospital Patient (uncredited)
Christopher Jason Brown
饰：Danny Trexler
乔·霍尔特
Joe Holt
饰：Transit Officer
Katya Abelski
饰：Rebecca Porter
B'Jahn
饰：Ward Patient
Anne Carroll
Anne Carroll
饰：Ward Patient
Leo Frank
饰：Ward Patient
Valerie Giocondo
饰：Ward Patient
William Godbolt
饰：Ward Patient
Ralph Hadida
饰：Ward Patient
Lydia Murray
饰：Ward Patient
Rafael Real
饰：Ward Patient
Julie Sands
饰：Ward Patient
Gene Smith
饰：Ward Patient
Paulo Pascoal
饰：Thief (uncredited)
Randy Springer
Randy Springer
饰：Lab Tech (uncredited)
安东尼·布拉德福德
Anthony Bradford
饰：演员 Actor/Actress
约瑟夫·史蒂文
Joseph Steven
饰：演员 Actor/Actress
文斯·库蓬
Vince Cupone
饰：演员 Actor/Actress
埃里克·拉雷·哈维
Erik LaRay Harvey
饰：Security Guard