Lexi Wolfe

饰：Miss Mary Morstan

Linda Jean Barry

饰：Mrs. Hudson

Ross K. Foad

饰：Sherlock Holmes

Adrian Charlton

饰：Professor James Moriarty

Kelsey Williams

饰：Gwendolyn Chambers

Michael Archer

饰：Dr John Hamish Watson

Amy L. Brunskill

饰：Jessica The Milk Maid

Clifford Hume

饰：Charles Augustus Milverton

Emma Lillie Lees

饰：Charlotte Chambers

托比·罗尔特

Toby Rolt

饰：Lord Boorswar

Martin W. Payne

饰：Experiment R

James Ian Gray

饰：Mycroft Holmes

Rosanna Smith

饰：Sister Abigail Bliss

彼得·斯坦福

Peter Stanford

饰：Inspector Bradstreet

Tony Carpenter

饰：Henry Boffy